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Publications（論文など）

Books（著書）　Patents（特許）

[111] Asymmetric autocatalysis with amplification of enantiomeric excess utilizing chiral crystals of achiral o-terphenyls as chiral triggers.
Tsuneomi Kawasaki, Daisuke Tateishi, Arimasa Matsumoto, Kenso Soai
Tetrahedron, 2024, 152(15 Feb), 133835.
DOI:10.1016/j.tet.2024.133835



[110] Achiral 2-pyridone and 4-aminopyridine act as chiral inducers of asymmetric autocatalysis with amplification of enantiomeric excess via the formation of chiral crystals.
Arimasa Matsumoto, Daisuke Tateishi, Tsuyoshi Nakajima, Shiori Kurosaki, Tomohiro Ogawa, Tsuneomi Kawasaki, Kenso Soai
Chirality, 2024, 36(1), e23617.
DOI: 10.1002/chir.23617



[109: Front cover, Open access] Chirally and chemically reversible Strecker reaction.
Yutaro Machida, Yudai Tanaka, Yuya Masuda, Aya Kimura, Tsuneomi Kawasaki
Chemical Science, 2023, 14(17), 4480-4484.
DOI: 10.1039/D3SC00359K





[108: Front cover, Open access] Asymmetric Strecker reaction at the solid/solid interface.
Yuki Yoshimura, Yudai Tanaka, Ryota Kobayashi, Kohei Niikura, Tsuneomi Kawasaki
Organic & Biomolecular Chemistry, 2023, 21(3), 520-524.
DOI: 10.1039/D2OB01802K




[107] キラリティの基礎および生命のホモキラリティの意義と起源
硤合憲三、川﨑常臣
化学と教育 (Chemistry and Education), 2022, 70(5), 254-257.

[106] Asymmetric Autocatalysis as an Efficient Link Between the Origin of Homochirality and Highly Enantioenriched Compounds.
Kenso Soai, Tsuneomi Kawasaki, Arimasa Matsumoto
Origins of Life and Evolution of Biospheres, 2022, 52, 57-74.
DOI: 10.1007/s11084-022-09626-7

[105: Supplementary Cover, Open access] Quantitative difference in solubility of diastereomeric (²H/¹H)-isotopomers.
Tsuneomi Kawasaki,* Hiroki Kubo, Satoshi Nishiyama, Taiki Saijo, Rintaro Yokoi, Yuji Tokunaga
Journal of the American Chemical Society, 2021, 143(46), 19525-19531.
DOI: 10.1021/jacs.1c09253





[104: Top Cited Article2021-2022] Asymmetric autocatalysis as a link between crystal chirality and highly enantioenriched organic compounds.
Kenso Soai*, Arimasa Matsumoto, Tsuneomi Kawasaki
Israel Journal of Chemistry, 2021, 61(9-10), 507-516.
DOI: 10.1002/ijch.202100047

[103: Front cover, Open access] Asymmetric autocatalysis triggered by triglycine sulfate with switchable chirality by altering the direction of the applied electric field.




[102] Synthesis, photochemical properties, and cytotoxicity of 10-alkylphenazin-2(10H)-ones.
Haruki Kohatsu, Shogo Kamo, Takuya Hosokai, Shinji Kamisuki, Yutaro Machida, Ryota Kobayashi, Tsuneomi Kawasaki, Kenji Ohgane, Kouji Kuramochi*
Heterocycles, 2021, 102(5), 871-885.
DOI: 10.3987/COM-21-14420

[101] Utilization of a crown ether/amine-type rotaxane as a probe for the versatile detection of anions and acids by thin-layer chromatography.
Shinobu Miyagawa, Masaki Kimura, Shin Kagami, Tsuneomi Kawasaki, Yuji Tokunaga*
Chemistry - An Asian Journal, 2020, 15(19), 3044-3049.
DOI: 10.1002/asia.202000746

[100] アミノ酸ホモキラリティの起源解明を目指して.
川﨑常臣
理大 科学フォーラム, 2020, 37(5), 52-53

[99] Investigation on the epoxidation of piperitenone, and structure–activity relationships of piperitenone oxide for differentiation-inducing activity.
Ryohei Sato, Azusa Sasaki, Yuko Mori, Mio Komai, Shogo Kamo, Mai Onuki, Takafumi Seki, Zen Kawabe, Shu Miyajima, Shusuke Tomoshige, Tsuneomi Kawasaki, Shuichi Sato, Takako Nakamura, Nakao Kubo, Seiji Takeda, Shuichi Date, Shigehisa Okamoto, Panida Boonyaritthongchai, Krit Thirapanmethee, Mullika Traidej Chomnawang, Bhanubong Bongcheewin, Thuy Linh Nguyen, Huong Lan Thi Nguyen, Huong Thi Le, Yasushi Nakamura,* Kouji Kuramochi*
Journal of Oleo Science, 2020, 69(8), 951-958.
DOI: 10.5650/jos.ess19278

[98] Rotaxanes comprising cyclic phenylenedioxydiacetamides and secondary mono- and bis-dialkylammonium ions: effect of macrocyclic ring size on pseudorotaxane formation.
Takanori Nakamura, Yuka Mori, Masaya Naito, Yukari Okuma, Shinobu Miyagawa, Hikaru Takaya, Tsuneomi Kawasaki, Yuji Tokunaga*
Organic Chemistry Frontiers, 2020, 7(3), 513-524.
DOI: 10.1039/C9QO01359H

[97] Studies toward the enantioselective synthesis of neurymenolide A: Construction of the macrocyclic core via Claisen rearrangement.
Masahiro Masuda, Natsuki Sakurai, Yusuke Ogura, Tetsuji Murase, Tsuneomi Kawasaki, Shohei Aiba, Naoki Mori, Hidenori Watanabe, Hirosato Takikawa*
Tetrahedron Letters, 2020, 61(18), 151825.
DOI: 10.1016/j.tetlet.2020.151825

[96] Synthesis of anti-Helicobacter pylori sesquiterpene employing tandem radical cyclization, and determination of the absolute configuration of the natural product.
Ken Ishigami,* Kazuki Kadowaki, Shinya Yamada, Shohei Aiba, Tsuneomi Kawasaki, Ryo Katsuta, Arata Yajima, Tomoo Nukada, Hirosato Takikawa, Hidenori Watanabe
Tetrahedron, 2020, 76(3), 130834.
DOI: 10.1016/j.tet.2019.130834

[95] Ring size affects the kinetic and thermodynamic formation of [2]rotaxanes featuring an unsymmetric bis-crown ether component.
Masaya Naito, Takaaki Fujino, Shinya Tajima, Shinobu Miyagawa, Kazuyuki Yoshida, Hajime Inoue, Hiroaki Takagawa, Tsuneomi Kawasaki, Yuji Tokunaga*
Materials Chemistry Frontiers, 2019, 3(12), 2702-2706.
DOI: 10.1039/C9QM00441F

[94] Self-replication of chiral α-amino acids in Strecker-type synthesis via asymmetric induction and amplification of their own chiral intermediate α-aminonitriles.
Shohei Aiba, Yudai Tanaka, Yuji Tokunaga, Tsuneomi Kawasaki*
Bulletin of the Chemical Society of Japan, 2019, 92(10), 1656-1661.
DOI: 10.1246/bcsj.20190116


[93: Symmetry 2021 Best Paper Awards / Editor's Choice] Role of asymmetric autocatalysis in the elucidation of origins of homochirality of organic compounds.
Kenso Soai,* Tsuneomi Kawasaki, Arimasa Matsumoto
Symmetry, 2019, 11(5), 694.
DOI: 10.3390/sym11050694
Symmetry 2021 Best Paper Awards [link]
Editor's Choice [link]

[92] Formation of enantioenriched alkanol with stochastic distribution of enantiomers in the absolute asymmetric synthesis under heterogeneous solid-vapor phase conditions.
Yoshiyasu Kaimori, Yui Hiyoshi, Tsuneomi Kawasaki, Arimasa Matsumoto, Kenso Soai*
Chemical Communications, 2019, 55(36), 5223-5226.
DOI: 10.1039/C9CC01875A

[91] Synthesis, antibacterial and cytotoxic evaluation of flavipucine and its derivatives.
Yasuha Kusakabe, Shoma Mizutani, Shogo Kamo, Tatsuki Yoshimoto; Shusuke Tomoshige, Tsuneomi Kawasaki, Ryoko Takasawa, Kazunori Tsubaki, Kouji Kuramochi*
Bioorganic & Medicinal Chemistry Letters, 2019, 29(11), 1390-1394.
DOI: 10.1016/j.bmcl.2019.03.034

[90: Open access] Achiral amino acid glycine acts as an origin of homochirality in asymmetric autocatalysis.
Arimasa Matsumoto, Hanae Ozaki, Sumeru Tsuchiya, Toru Asahi, Meir Lahav, Tsuneomi Kawasaki, Kenso Soai*
Organic & Biomolecular Chemistry, 2019, 17(17), 4200-4203.
DOI: 10.1039/c9ob00345b


[89] Rotational isomerism of the amide units in rotaxanes based on a cyclic tetraamide and secondary ammonium ions.
Yukari Okuma, Toshihiro Tsukamoto, Takayuki Inagaki, Shinobu Miyagawa, Masaki Kimura, Masaya Naito, Hikaru Takaya, Tsuneomi Kawasaki, Yuji Tokunaga*
Organic Chemistry Frontiers, 2019, 6(7), 1002-1009.
DOI: 10.1039/C9QO00096H

[88] Absolute asymmetric Strecker synthesis in a mixed aqueous medium: Reliable access to enantioenriched α-aminonitrile.
Shinobu Miyagawa, Shohei Aiba, Hajime Kawamoto, Yuji Tokunaga, Tsuneomi Kawasaki*
Organic & Biomolecular Chemistry, 2019, 17(5), 1238-1244.
DOI: 10.1039/C8OB03092H


[87] 研究室便り 東京理科大学理学部応用化学科 川﨑研究室
川﨑常臣
有機結晶部会ニュースレター, 2018, (43), 137-138.

[86] Recognition behavior of a porphyrin hetero‐dimer self‐assembled through an amidinium‐carboxylate salt bridge.
Masaki Kimura, Jyunichi Miyashita, Shinobu Miyagawa, Tsuneomi Kawasaki, Hikaru Takaya, Yuji Tokunaga*
Asian Journal of Organic Chemistry, 2018, 7(10), 2087-2093.
DOI: 10.1002/ajoc.201800382

[85] Synthesis of a chiral [2]rotaxane: Induction of a helical structure through double threading.
Toshihiro Tsukamoto, Ryota Sasahara, Atsuya Muranaka,* Yuzuki Miura, Yu Suzuki, Masaki Kimura, Shinobu Miyagawa, Tsuneomi Kawasaki, Nagao Kobayashi, Masanobu Uchiyama, Yuji Tokunaga*
Organic Letters, 2018, 20(16), 4745-4748.
DOI: 10.1021/acs.orglett.8b01727

[84] Asymmetric autocatalysis of pyrimidyl alkanol and related compounds. Self-replication, amplification of chirality and implication for the origin of biological enantioenriched chirality.
Kenso Soai,* Tsuneomi Kawasaki, Arimasa Matsumoto
Tetrahedron, 2018, 74(16), 1973-1990.
DOI: 10.1016/j.tet.2018.02.040

[83] Formation of [2]- and [3]rotaxanes through bridging under kinetic and thermodynamic control.
Takaaki Fujino, Hirotake Naitoh, Shinobu Miyagawa, Masaki Kimura, Tsuneomi Kawasaki, Kazuyuki Yoshida, Hajime Inoue, Hiroaki Takagawa, Yuji Tokunaga*
Organic Letters, 2018, 20 (2), 369-372.
DOI: 10.1021/acs.orglett.7b03615

[82: Cover picture] Highly stereoselective Strecker synthesis induced by the slight modification of benzhydrylamine from achiral to chiral.
Naoya Takamatsu, Shohei Aiba, Takuya Yamada, Yuji Tokunaga, Tsuneomi Kawasaki*
Chemistry - A European Journal, 2018, 24(6), 1304-1310.
DOI: 10.1002/chem.201704033
Cover Picture (pp. 1218), DOI: 10.1002/chem.201705072



[81] Four-state molecular shuttling of [2]rotaxanes in response to acid/base and alkali-metal cation stimuli.
Masaki Kimura, Takuma Mizuno, Masahiro Ueda, Shinobu Miyagawa, Tsuneomi Kawasaki, Yuji Tokunaga*
Chemistry An Asian Journal, 2017, 12, 1381-1390.
DOI: 10.1002/asia.201700493

[80] Asymmetric Strecker reaction arising from the molecular orientation of an achiral imine at the single-crystal face: Enantioenriched L- and D-amino acids.
Shinobu Miyagawa, Koji Yoshimura, Yusuke Yamazaki, Naoya Takamatsu, Tetsuya Kuraishi, Shohei Aiba, Yuji Tokunaga, Tsuneomi Kawasaki*
Angewandte Chemie, 2017, 129(4), 1075–1078.
DOI: 10.1002/ange.201611128
Angewandte Chemie International Edition, 2017, 56(4), 1055-1058.
DOI: 10.1002/anie.201611128


[79] Achiral inorganic gypsum acts as an origin of chirality through its enantiotopic surface in conjunction with asymmetric autocatalysis.
Arimasa Matsumoto, Yoshiyasu Kaimori, Mizuki Uchida, Haruna Omori, Tsuneomi Kawasaki, Kenso Soai*
Angewandte Chemie International Edition, 2017, 56(2), 545-548.
DOI: 10.1002/anie.201610099

[78] Point-to-point ultra-remote asymmetric control with flexible linker.
Tsuneomi Kawasaki, Yasuyuki Ishikawa, Yoshihiro Minato, Takashi Otsuka, Shigeru Yonekubo, Itaru Sato, Takanori Shibata, Arimasa Matsumoto, Kenso Soai*
Chemistry A European Journal, 2017, 23(2), 282-285.
DOI: 10.1002/chem.201605076


[77: Inside front cover, Open access] Replication of α-amino acids via Strecker synthesis with amplification and multiplication of chiral intermediate aminonitriles.
Shohei Aiba, Naoya Takamatsu, Taichiro Sasai, Yuji Tokunaga, Tsuneomi Kawasaki*
Chemical Communications, 2016, 52(72), 10834-10837.
DOI: 10.1039/C6CC05544C
Inside front cover
DOI: 10.1039/C6CC90400A


(1) 朝日新聞DIGITAL（福井）2016年9月17日
(2) 朝日新聞（24面（福井））2016年9月17日
(3) 中日新聞（福井総合19面）2016年9月8日
(4) 日刊県民福井（ふくい総合）2016年9月8日
(5) 福井新聞（26面）2016年9月7日
(6) NHK NEWS WEB（福井県のニュース　福井放送局）2016年9月7日
(7) NHK総合「ニュースザウルス福井」2016年9月6日



[76: VIP, Cover Picture, Open access] Asymmetric induction by nitrogen ¹⁴N/¹⁵N isotopomer in conjunction with asymmetric autocatalysis.
Arimasa Matsumoto,* Hanae Ozaki, Shunya Harada, Kyohei Tada, Tomohiro Ayugase, Hitomi Ozawa, Tsuneomi Kawasaki, Kenso Soai*
Angewandte Chemie International Edition, 2016, 55(49), 15246-15249 .
DOI: 10.1002/anie.201608955
Cover Picture
DOI: 10.1002/anie.201610382


[75: Selected paper, Open access] Elucidation of the structures of asymmetric autocatalyst based on X-ray crystallography.
Arimasa Matsumoto,* Satoshi Fujiwara, Takaaki Abe, Atsushi Hara, Takayuki Tobita, Taisuke Sasagawa, Tsuneomi Kawasaki,* Kenso Soai*
Bulletin of the Chemical Society of Japan, 2016, 89(10), 1170-1177.
DOI: 10.1246/bcsj.20160160

[74] Five-state molecular shuttling of a pair of [2]rotaxanes: Distinct outputs in response to acid and base stimuli.
Masahiro Ueda, Shyoya Terazawa, Yasuaki Deguchi, Masaki Kimura, Naoki Matsubara, Shinobu Miyagawa, Tsuneomi Kawasaki, Yuji Tokunaga*
Chemistry An Asian Journal, 2016, 11(16), 2291-2300.
DOI: 10.1002/asia.201600743

[73] 結晶化による不斉発生と増幅を用いたキラル有機化合物の合成
川﨑常臣、髙松直矢、會場翔平
ファインケミカル, 2016, 45(2), 50-57.

[72] Base–acid-induced translational isomerism in a branched [4]rotaxane.
Yuji Tokunaga,* Masaki Kimura, Masahiro Ueda, Shinobu Miyagawa, Tsuneomi Kawasaki, Kenji Hisada*
Tetrahedron Letters, 2016, 57(10), 1120-1123.
DOI: 10.1016/j.tetlet.2016.01.096

[71: Open access] Crystal structure of isopropylzinc alkoxide of pyrimidyl alkanol: mechanistic insights for asymmetric autocatalysis with amplification of enantiomeric excess.
Arimasa Matsumoto,* Takaaki Abe, Atsushi Hara, Takayuki Tobita, Taisuke Sasagawa, Tsuneomi Kawasaki,* Kenso Soai*
Angewandte Chemie International Edition, 2015, 54(50), 15218-15221.
DOI: 10.1002/anie.201508036

[70] Spontaneous formation and amplification of an enantioenriched α-amino nitrile: a chiral precursor for Strecker amino acid synthesis.
Tsuneomi Kawasaki,* Naoya Takamatsu, Shohei Aiba, Yuji Tokunaga
Chemical Communications, 2015, 51(76), 14377-14380.
DOI: 10.1039/C5CC05848A


[69: Front cover, Open access] Helical mesoporous silica as an inorganic heterogeneous chiral trigger for asymmetric autocatalysis with amplification of enantiomeric excess.
Tsuneomi Kawasaki, Yuko Araki, Kunihiko Hatase, Kenta Suzuki, Arimasa Matsumoto, Toshiyuki Yokoi, Yoshihiro Kubota, Takashi Tatsumi,* Kenso Soai*
Chemical Communicaations, 2015, 51(42), 8742-8744.
DOI: 10.1039/C5CC01750E
Front cover
DOI: 10.1039/C5CC90223A



[68] 不斉自己触媒反応を用いたキラル化学—同位体置換キラル化合物が誘起するエナンチオ選択的反応—
川﨑常臣、松本有正、硤合憲三
化学工業, 2015, 66(2), 49-54.

[67] Multi-state molecular shuttling of a pair of [2]rotaxane in response
Yuji Tokunaga,* Hajime Kawamoto, Hiroshi Ohsaki, Masaki Kimura, Shinobu Miyagawa, Yasuaki Deguchi, Tsuneomi Kawasaki
Tetrahedron Letters, 2015, 56(13), 1667-1670.
DOI: 10.1016/j.tetlet.2015.02.035

[66] Asymmetric autocatalysis of pyrimidyl alkanol and its application to the study on the origin of homochirality.
Kenso Soai,* Tsuneomi Kawasaki, Arimasa Matsumoto
Accounts of Chemical Research, 2014, 47(12), 3643-3654.
DOI: 10.1021/ar5003208

[65] Self-replication and amplification of enantiomeric excess of chiral multifunctionalized large molecules by asymmetric autocatalysis.
Tsuneomi Kawasaki, Mai Nakaoda, Yutaro Takahashi, Yusuke Kanto, Nanako Kuruhara, Kenji Hosoi, Itaru Sato, Arimasa Matsumoto, Kenso Soai*
Angewandte Chemie International Edition, 2014, 53(42), 11199-11202.
DOI: 10.1002/anie.201405441


[64] The Origins of homochirality examined by using asymmetric autocatalysis
Kenso Soai, Tsuneomi Kawasaki, Arimasa Matsumoto
The Chemical Record, 2014, 14(1), 70-83.
DOI: 10.1002/tcr.201300028

[63] Five-state molecular switching of a [3]rotaxane in response to weak and strong acid and base stimuli
Yuji. Tokunaga,* S. Ikezaki, M. Kimura, K. Hisada, T. Kawasaki
Chemical Communications, 2013, 49(100), 11749-11751.
DOI: 10.1039/c3cc47343k

[62] Formation of pseudo[3]rotaxanes containing calix-bis-crowns and secondary ammonium ions and their thermodynamic stabilities in a solution: Preorganization by second macrocycle and nonallosteric behavior exhibited by large crown cavities
Yuji Tokunaga,* Kentaroh Hayakawa, Junichi Miyashita, Tsuneomi Kawasaki, Sinobu Miyagawa
Tetrahedron Letters, 2013, 54(50), 6829-6833.
DOI: 10.1016/j.tetlet.2013.10.015

[61] Enantiodivergent formation of a chiral cytosine crystal by removal of crystal water from an achiral monohydrate crystal under reduced pressure.
Hiroko Mineki, Yoshiyasu Kaimori, Tsuneomi Kawasaki, Arimasa Matsumoto, Kenso Soai*
Tetrahedron: Asymmetry, 2013, 24(21-22), 1365-1367.
DOI: 10.1016/j.tetasy.2013.09.020


[60: Hot paper] Asymmetric autocatalysis induced by cinnabar: observation of the enantioselective adsorption of a 5-pyrimidyl alkanol on the crystal surface.
Hitoshi Shindo,* Yusuke Shirota, Kaori Niki, Tsuneomi Kawasaki, Kenta Suzuki, Yuko Araki, Arimasa Matsumoto, Kenso Soai*
Angewandte Chemie International Edition, 2013, 52(35), 9135-9138.
DOI: 10.1002/anie.201304284


[59: Editor's choice, Open access] Enantioselective synthesis induced by the helical molecular arrangement in the chiral crystal of achiral tris(2-hydroxyethyl) 1,3,5-benzenetricarboxylate in conjunction with asymmetric autocatalysis.
Tsuneomi Kawasaki,* Mizuki Uchida, Yoshiyasu Kaimori, Taisuke Sasagawa, Arimasa Matsumoto, Kenso Soai*
Chemistry Letters, 2013, 42(7), 711-713.
DOI: 10.1246/cl.130185


[58: Inside front cover] Asymmetric autocatalysis triggered by oxygen isotopically chiral glycerin.
Arimasa Matsumoto, Shotaro Oji, Shizuka Takano, Kyohei Tada, Tsuneomi Kawasaki, Kenso Soai*
Organic & Biomolecular Chemistry, 2013, 11(18), 2928-2931.
DOI: 10.1039/C3OB40293B


[57] 不斉の起源解明への有機合成化学的アプローチ：不斉増幅する不斉自己触媒反応
川﨑常臣、佐藤格、峯木紘子、松本有正、硤合憲三
有機合成化学協会誌, 2013, 71(2), 109-123.
DOI: 10.5059/yukigoseikyokaishi.71.109


[56] Asymmetric autocatalysis of pyrimidyl alkanol.
Kenso Soai,* Tsuneomi Kawasaki
Topics in Organometallic Chemistry, 2013, 44(Volume title: Inventing Reactions), 261-279.
DOI: 10.1007/3418_2012_48

[55] 不斉自己触媒反応とキラル有機化合物の不斉の起源
川﨑常臣, 硤合憲三
Organometallic News, 2012, (2), 36-41.

[54] Asymmetric autocatalysis. Pathway to the biological homochirality.
Tsuneomi Kawasaki, Arimasa Matsumoto, Kenso Soai*
Chimica Oggi/Chemistry Today, 2012, 30(5), 10-23.

[53] Asymmetric autocatalysis initiated by achiral nucleic acid base adenine: implications on the origin of homochirality of biomolecules.
Hiroko Mineki, Taichi Hanasaki, Arimasa Matsumoto, Tsuneomi Kawasaki,* Kenso Soai*
Chemical Communications, 2012, 48(85), 10538-10540.
DOI: 10.1039/C2CC34928K


[52] Reversal in enantioselectivity induced by achiral alcohols in asymmetric autocatalysis in the presence of a chiral diol as a chiral initiator
Takanori Shibata,* Hikaru Tarumi, Tsuneomi Kawasaki, Kenso Soai
Tetrahedron: Asymmetry, 2012, 23(14), 1023-1027.
DOI: 10.1016/j.tetasy.2012.07.010

[51] Asymmetric autocatalysis triggered by chiral crystals formed from achiral compounds and chiral isotopomers.
Tsuneomi Kawasaki, Kenso Soai*
Israel Journal of Chemistry 2012, 52(7) 582-590.
DOI: 10.1002/ijch.201100155

[50] Absolute chirality of the gamma-polymorph of glycine: correlation of the absolute structure with the optical rotation.
Kazuhiko Ishikawa, Masahito Tanaka, Toshiya Suzuki, Akiko Sekine, Tsuneomi Kawasaki, Kenso Soai, Motoo Shiro, Meir Lahav, Toru Asahi
Chemical Communications, 2012, 48(48), 6031-6033.
DOI: 10.1039/C2CC30549F

[49] 右手と左手の化学 ―不斉自己触媒反応を用いる不斉の起源解明と高感度キラル認識―
川﨑常臣, 硤合憲三
理大　科学フォーラム, 2012, 29(4), 24-29.

[48] Prediction of Soai reaction enantioselectivity induced by crystals of N-(2-thienylcarbonyl)glycine.
Damien J. Carter, Andrew L. Rohl, Alexander Shtukenberg, Shudan Bian, Chunhua Hu, Lisa Baylon, Bart Kahr, Hiroko Mineki, Koichiro Abe, Tsuneomi Kawasaki, Kenso Soai
Crystal Growth & Design, 2012, 12(4), 2138-2145.
DOI: 10.1021/cg300207d

[47] アキラル化合物の結晶化によるキラリティー発生と キラル有機結晶を不斉源とする不斉自己触媒反応
川﨑常臣、硤合憲三
日本結晶学会誌, 2011, 53(3), 201-206.

[46] キラル分子の不斉起源とホモキラリティーの謎に迫る
硤合憲三、川﨑常臣
化学, 2011, 66(8), 49-53.

[45] Asymmetric induction arising from enantiomerically enriched carbon-13 isotopomers and highly sensitive chiral discrimination by asymmetric autocatalysis.
Tsuneomi Kawasaki,* Kenso Soai*
Bulletin of the Chemical Society of Japan, 2011, 84(9), 879-892.
DOI: 10.1246/bcsj.20110120

[44] Asymmetric autocatalysis: triggered by chiral isotopomer arising from oxygen isotope substitution.
Tsuneomi Kawasaki,* Yasushi Okano, Etsuharu Suzuki, Shizuka Takano, Shotaro Oji, Kenso Soai*
Angewandte Chemie International Edition, 2011, 50(35), 8131-8133.
DOI: 10.1002/anie.201102263


[43: Open access] Enantioselective C-C bond formation as a result of the oriented prochirality of an achiral aldehyde at the single-crystal face upon treatment with a dialkyl zinc vapor.
Tsuneomi Kawasaki,* Sayaka Kamimura, Ai Amihara, Kenta Suzuki, Kenso Soai*
Angewandte Chemie International Edition, 2011, 50(30), 6796-6798.
DOI: 10.1002/anie.201102031


[42] Reversal phenomenon of enantioface selectivity by the cooperative operation of two chiral catalysts.
Tsuneomi Kawasaki,* Yuki Wakushima, Mai Asahina, Kazuya Shiozawa, Tomoyuki Kinoshita, Francois Lutz, Kenso Soai*
Chemical Communications, 2011, 47(18), 5277-5279.
DOI: 10.1039/C1CC10136F


[41] Enantioselective synthesis induced by chiral crystal composed of DL-serine in conjunction with asymmetric autocatalysis.
Tsuneomi Kawasaki,* Taisuke Sasagawa, Kazuya Shiozawa, Mizuki Uchida, Kenta Suzuki, Kenso Soai*
Organic Letters, 2011, 13(9), 2361-2363.
DOI: 10.1021/ol200616t


[40: Editor's choice, Open access] Enantioselective synthesis induced by compounds with chirality arising from partially deuterated methyl groups in conjunction with asymmetric autocatalysis
Tsuneomi Kawasaki,* Hitomi Ozawa, Masateru Ito, Kenso Soai*
Chemistry Letters, 2011, 40(3), 320-321.
DOI: 10.1246/cl.2011.320


[39: Open access] Spontaneous absolute asymmetric synthesis promoted by achiral amines in conjunction with asymmetric autocatalysis
Kenta Suzuki, Kunihiko Hatase, Daisuke Nishiyama, Tsuneomi Kawasaki, Kenso Soai*
Journal of Systems Chemistry, 2010, 1, 5.
DOI: 10.1186/1759-2208-1-5

[38] Amplification of chirality as a pathway to biological homochirality
Tsuneomi Kawasaki,* Kenso Soai*
Journal of Fluorine Chemistry, 2010, 131(4), 525-534.
DOI: 10.1016/j.jfluchem.2009.12.014

[37: ACS AuthorChoice, Open access] Generation of absolute controlled crystal chirality by the removal of crystal water from achiral crystal of nucleobase cytosine
Tsuneomi Kawasaki, Yuko Hakoda, Hiroko Mineki, Kenta Suzuki, Kenso Soai*
Journal of the American Chemical Society, 2010, 132(9), 2874-2875.
DOI: 10.1021/ja1000938


[36] Asymmetric autocatalysis induced by chiral crystals of achiral tetraphenylethylenes.
Tsuneomi Kawasaki, Mai Nakaoda, Nobuhiro Kaito, Taisuke Sasagawa, Kenso Soai*
Origins of Life and Evolution of the Biosphere, 2010, 40(1), 65-78.
DOI: 10.1007/s11084-009-9183-4

[35] 展望：同位体不斉が引き起こす不斉自己触媒反応－ホモキラリティーの起源としての同位体不斉－
川崎常臣、硤合憲三
Isotope News, 2009, 667(11), 2-6.

[34] Asymmetric autocatalysis. Automultiplication of chiral molecules
Tsuneomi Kawasaki, Kenso Soai
Chimica Oggi/Chemistry Today, 2009, 27(6, suppl), 3-7.

[33] Discrimination of cryptochirality in chiral isotactic polystyrene by asymmetric autocatalysis.
Tsuneomi Kawasaki, Christiane Hohberger, Yuko Araki, Kunihiko Hatase, Klaus Beckerle, Jun Okuda,* Kenso Soai*
Chemical Communications, 2009, (37), 5621-5623.
DOI: 10.1039/b912813a

[32] 炭素同位体（¹³C/¹²C）置換キラル化合物による不斉合成―不斉自己触媒反応を用いて―
川崎常臣
化学と工業, 2009, 62(8), 898-900.

[31] Asymmetric autocatalysis triggered by carbon isotope (¹³C/¹²C) chirality.
Tsuneomi Kawasaki, Yukari Matsumura, Takashi Tsutsumi, Kenta Suzuki, Masateru Ito, Kenso Soai*
Science, 2009, 324(5926), 492-495.
DOI: 10.1126/science.1170322
Picked up:
(1) C&EN 2009, 87(13), 29. [March 30, 2009; Science & Technology Concentrates]
(2) Synfacts 2009, 2009(08), 0760.
(3) Nature Chemistry [Research Highlights]
(4) Synform 2009/06.
(5) 朝日新聞25面（2009年4月24日）
(6) 日経産業新聞10面（2009年3月30日）
(7) NewScientist, 2010, 15 May, 31.

[30] 研究室紹介　ー北から南からー
硤合憲三、川崎常臣
Organometallic News, 2009, (1), 20-21.

[29: Front cover] Highly enantioselective asymmetric autocatalysis using chiral ruthenium complex-ion-exchanged synthetic hectorite as a chiral initiator.
Tsuneomi Kawasaki, Toshiki Omine, Kenta Suzuki, Hisako Sato, Akihiko Yamagishi, Kenso Soai
Organic & Biomolecular Chemistry, 2009, 7(6), 1073-1075.
DOI: 10.1039/b823282b
Front cover
DOI: 10.1039/B903491A


[28] Asymmetric autocatalysis induced by meteoritic amino acids with hydrogen isotope chirality.
Tsuneomi Kawasaki, Masako Shimizu, Daisuke Nishiyama, Masateru Ito, Hitomi Ozawa, Kenso Soai*
Chemical Communications, 2009, (29), 4396-4398.
DOI: 10.1039/b908754k
Picked up:
(1) Highlights in Chemical Science 2009, 6(8), C60.
(2) 2009 ChemComm web theme issue: "Selective Catalysis for Organic Synthesis"


[27] 不斉現象に新事実　炭素同位体で光学活性体に偏りが生じる！
硤合憲三、川崎常臣
化学, 2009, 64(10), 38-43.

[26] Enantioselective synthesis utilizing enantiomorphous organic crystal of achiral benzils as a source of chirality in asymmetric autocatalysis.
Tsuneomi Kawasaki, Yuuki Harada, Kenta Suzuki, Takayuki Tobita, Nicola Florini, Gyula Pályi, Kenso Soai*
Organic Letters, 2008, 10(18), 4085-4088.
DOI: 10.1021/ol801600y


[25] 不斉自己触媒反応を用いて不斉の起源に迫る
硤合憲三、川崎常臣
化学と教育, 2008, 56(8), 384-385.

[24] ホモキラリティーの起源解明への化学的アプローチー不斉自己触媒反応を用いてー
硤合憲三、川崎常臣
ファインケミカル, 2008, 37, 5-16.

[23] Mechanistic insights in the reversal of enantioselectivity of chiral catalysts by achiral catalysts in asymmetric autocatalysis.
François Lutz, Takashi Igarashi, Tomoyuki Kinoshita, Mai Asahina, Koichi Tsukiyama, Tsuneomi Kawasaki, Kenso Soai*
Journal of the American Chemical Society, 2008, 130(10), 2956-2958.
DOI: 10.1021/ja077156k

[22] Achiral nucleobase cytosine acts as an origin of homochirality of biomolecules in conjunction with asymmetric autocatalysis.
Tsuneomi Kawasaki, Kenta Suzuki, Yuko Hakoda, Kenso Soai*
Angewandte Chemie International Edition 2008, 47(3) 496-499.
DOI: 10.1002/anie.200703634

[21] Asymmetric autocatalysis with amplification of chirality.
Kenso Soai,* Tsuneomi Kawasaki
Topics in Current Chemistry, 2008, 284(Amplification of chirality), 1-33.
DOI: 10.1007/128_2007_138

[20] Chiral secondary alcohol-induced asymmetric autocatalysis: correlation between the absolute configuration of the chiral initiators and the product.
Takanori Shibata,* Kimiko Iwahashi, Tsuneomi Kawasaki, Kenso Soai
Tetrahedron: Asymmetry, 2007, 18(15), 1759-1762.
DOI: 10.1016/j.tetasy.2007.07.030

[19] Determination of absolute configurations of amino acids by asymmetric autocatalysis of 2-alkynylpyrimidyl alkanol as a chiral sensor.
Itaru Sato, Yasushi Ohgo, Hirotaka Igarashi, Daisuke Nishiyama, Tsuneomi Kawasaki, Kenso Soai*
Journal of Organometallic Chemistry, 2007, 692(9), 1783-1787.
DOI: 10.1016/j.jorganchem.2006.11.042

[18] Asymmetric autocatalysis induced by octahedral tris(acetylacetonato)chromium(III) complex as a homogeneous chiral initiator.
Tsuneomi Kawasaki, Toshiki Omine, Mirai Sato, Yosuke Morishita, Kenso Soai*
Chemistry Letters, 2007, 36(1), 30-31.
DOI: 10.1246/cl.2007.30

[17] The distribution of chiral asymmetry in meteorites: An investigation using asymmetric autocatalytic chiral sensors.
Tsuneomi Kawasaki, Kunihiko Hatase, Yusuke Fujii, Kazumichi Jo, Kenso Soai,* Sandra Pizzarello*
Geochimica et Cosmochimica Acta, 2006, 70(21), 5395-5402.
DOI: 10.1016/j.gca.2006.08.006

[16] Enantioselective synthesis induced by tetrathia-[7]-helicenes in conjunction with asymmetric autocatalysis
Tsuneomi Kawasaki, Kenta Suzuki, Emanuela Licandro, Alberto Bossi, Stefano Maiorana,* Kenso Soai*
Tetrahedron: Asymmetry, 2006, 17(14), 2050-2053.
DOI: 10.1016/j.tetasy.2006.07.015

[15] 不斉自己触媒反応とホモキラリティーの起源
Tsuneomi Kawasaki, Kenso Soai
触媒, 2006, 48(5), 346-352.

[14] Spontaneous absolute asymmetric synthesis in the presence of achiral silica gel in conjunction with asymmetric autocatalysis
Tsuneomi Kawasaki, Kenta Suzuki, Masako Shimizu, Keisuke Ishikawa, Kenso Soai*
Chirality, 2006, 18(7), 479-482.
DOI: 10.1002/chir.20273

[13] Chiral discrimination of cryptochiral saturated quaternary and tertiary hydrocarbons by asymmetric autocatalysis.
Tsuneomi Kawasaki, Hiroyuki Tanaka, Takashi Tsutsumi, Toshinari Kasahara, Itaru Sato, Kenso Soai*
Journal of the American Chemical Society, 2006, 128(18), 6032-6033.
DOI: 10.1021/ja061429e


[12] Enantioselective synthesis mediated by chiral crystal of achiral hippuric acid in conjunction with asymmetric autocatalysis.
Tsuneomi Kawasaki, Kenta Suzuki, Kunihiko Hatase, Masanari Otsuka, Hideko Koshima, Kenso Soai*
Chemical Communications, 2006, (17), 1869-1871.
DOI: 10.1039/B602442D


[11] Discovery of asymmetric autocatalysis with amplification of chirality and its implication in chiral homogeneity of biomolecules.
Kenso Soai,* Tsuneomi Kawasaki
Chirality, 2006, 18(7), 469-478.
DOI: 10.1002/chir.20289

[10] Asymmetric autocatalysis of a ferrocene-containing chiral compound with amplification of chirality.
François Lutz, Tsuneomi Kawasaki, Kenso Soai*
Tetrahedron: Asymmetry, 2006, 17(4), 486-490.
DOI: 10.1016/j.tetasy.2006.01.022

[9] Small amounts of chiral β-amino alcohols reverse the enantioselectivity of chiral catalysts in cooperative asymmetric autocatalysis.
François Lutz, Takashi Igarashi, Tsuneomi Kawasaki, Kenso Soai*
Journal of the American Chemical Society, 2005, 127(35), 12206-12207.
DOI: 10.1021/ja054323c

[8] Screening of putative oxygenase genes in the fusarium graminearum genome sequence database for their role in trichothecene biosynthesis.
Takeshi Tokai, Hiroyuki Koshino, Tsuneomi Kawasaki, Tomoko Igawa, Yoshikatsu Suzuki, Masayuki Sato, Makoto Fujimura, Takayoshi Eizuka, Hidenori Watanabe, Takeshi Kitahara, Kunihiro Ohta, Takehiko Shibata, Toshiaki Kudo, Hirokazu Inoue, Isamu Yamaguchi, Makoto Kimura*
FEMS Microbiology Letters, 2005, 251(2), 193-201.
DOI: 10.1016/j.femsle.2005.07.043

[7] Asymmetric amplification using chiral co-crystal formed from achiral organic molecules by asymmetric autocatalysis.
Tsuneomi Kawasaki, Kazumichi Jo, Hirotaka Igarashi, Itaru Sato, Masaki Nagano, Hideko Koshima, Kenso Soai*
Angewandte Chemie International Edition, 2005, 44(18), 2774-2777.
DOI: 10.1002/anie.200462963


[6] Enantioselective synthesis of near enantiopure compound by asymmetric autocatalysis triggered by asymmetric photolysis with circularly polarized light
Tsuneomi Kawasaki, Mirai Sato, Saori Ishiguro, Takahiro Saito, Yosuke Morishita, Itaru Sato, Hideo Nishino, Yoshihisa Inoue, Kenso Soai*
Journal of the American Chemical Society, 2005, 127(10), 3274-3275.
DOI: 10.1021/ja0422108


[5] Enantioselective synthesis induced by chiral epoxides in conjunction with asymmetric autocatalysis.
Tsuneomi Kawasaki, Masako Shimizu, Kenta Suzuki, Itaru Sato, Kenso Soai*
Tetrahedron: Asymmetry, 2004, 15(23), 3699-3701.
DOI: 10.1016/j.tetasy.2004.09.036


[4] Enantioselective synthesis induced by chiral organic-inorganic hybrid silsesquioxane In conjunction with asymmetric autocatalysis.
Tsuneomi Kawasaki, Keisuke Ishikawa, Hiromitsu Sekibata, Itaru Sato, Kenso Soai*
Tetrahedron Letters, 2004, 45(42), 7939-7941.
DOI: 10.1016/j.tetlet.2004.08.135


[3] Asymmetric autocatalysis initiated by chiral ephedrine immobilized on silica gel in a diisopropylzinc addition to pyrimidine-5-carbaldehyde.
Itaru Sato, Masako Shimizu, Tsuneomi Kawasaki, Kenso Soai*
Bulletin of the Chemical Society of Japan, 2004, 77(8), 1587-1588.
DOI: 10.1246/bcsj.77.1587

[2] Enantioselective synthesis of substituted 3-quinolyl alkanols and their application to asymmetric autocatalysis.
Itaru Sato, Tomohiko Nakao, Rie Sugie, Tsuneomi Kawasaki, Kenso Soai*
Synthesis, 2004, (9), 1419-1328.
DOI: 10.1055/s-2004-822402

[1] Total synthesis of (±)-cocculolidine.
Tsuneomi Kawasaki, Naoko Onoda, Hidenori Watanabe, Takeshi Kitahara*
Tetrahedron Letters, 2001, 42(45), 8003-8006.
DOI: 10.1016/S0040-4039(01)01650-1





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